ML ups the security ante and the root Library, by default, can't be accessed by programs the way they used to (at least I experienced it with i1 Profiler). If you select the Library folder and Get Info, you can go to Sharing & Permissions, add yourself as a user and give yourself Read/Write privileges. Then go to the colorsync folder within the library folder, do the same thing, but also click on the cogwheel and select "Apply to enclosed items. . . " That may help though I would have thought it could have defaulted to your user directory. Once I performed those actions, i1Profiler can once again write profiles in the root Library instead of just in my user library.