I would appreciate some simple things, so simple maybe they are impossible?
Toggle between "Auto Sync" and "Sync" in develop mode with one hot key, may I suggest "x". (Please, anything that requires 4 keys in combination is not a short cut.)
Ability to move both side panels to a second monitor. More options for using two monitors.
The ability to ignore drive letter (use volume name) for external drives with windows. This may be a windows problem?
Convert stacks to layers and a mask or reversible eraser tool.
All the suggestions I've seen posted here sound good, but don't want to see the program bog down and run slower. My pc 2 years old; 4.3 is running nicely. I want to get at least 2 more years out of it. I love the brush and gradient tools, but I don't ever want to go back to how slow and buggy they were when they were new.