I think that even negative film can be problematic. I did a test with Ektar 100 and got obscene colors. The reason is probably that blue channels is exceeding the DR of my scanner. The enclosed figure stops at D=3.0 but I think the channel goes much higher.
That Blue channel D-max is not an issue, provided that your scanner adjusts the exposure time of each channel properly/individually to neutralize the mask. It's the difference between the D-max and D-min for each channel that should be handled by the scanner's dynamic range capabilities.
Without proper mask elimination by tuned exposure times, all bets for good color are off.