If I open even one file and then close PS, I get Windows Error:
Adobe Photoshop CS6 has stopped working.
-> Check online for a solution and close the program
-> Close the program
The problem event name is APPCRASH.
Has anyone here experienced and resolved this issue? This is a 100% event for me.
Sorry, I can't help with that because I do not experience such behavior. All I can suggest is to make sure that your Graphics card drivers are up-to-date and your card is on the list of suggested ones (if not, deactivate GPU support and see if that makes a difference), and cables to external drives are of decent quality.
Today Adobe released an update to a number of applications, you may want to check if that helps in anyway.