It should not be necessary to do anything with printer drivers to install SilverFast 8. You would not be printing from SilverFast anyhow. It should only be necessary that the scanner driver is compliant with your operating system. I forget whether SilverFast 8 for Epson carries its own driver, or you need to install an Epson scanner driver, and I'm not anywhere near my Epson scanner to be able to refresh my mind on this. Here's what I recommend you do: install SilverFast 8, open it, see whether the Start dialog either shows your Epson scanner in the pane, or you need to dropdown the pane and select the Epson scanner (if it is there), then click start and see whether SilverFast drives your scanner. If it does, you re good to go. If it does not, go to the Epson website, find the scanner model and download and install Epson Scan or the bespoke scanner driver - whatever it is they provide. Then SilverFast will work for sure.