Yes, I use it with ADC checked on my HP LP2475w. It winds the brightness control in the monitor up, but achieves my specified brightness of 100cd/m2. Checking the resulting calibration/profiling performance with Colorimetre HCFR it seems to produce a reasonable calibration (better than the Eye One Display 2 I used to use). However, I've not tried it without ADC checked, so I can't tell you how it compares!