It's inefficient to put 6x6 lenses on a 645 camera. They will be heavier than they need to be.
Firstly for digital, te sensor formats are going to stay at 645 or smaller (currently 54x40mm actually), so a new 6x6 format body would not help there; it would only be relevant to film users, and I see no hope of a new camera design effort solely for the sake of 6x6 format film users.
But more importantly, the fear of a weight difference is probably unfounded because most optical designs would not differ significantly between 6x6 and 645 format, except perhaps the choice of focal lengths. In most cases, lenses of a given focal length and minimum f-stop for different formats do not vary much in optical design so long as the FOV is about normal or narrower; designs change mainly when wide-angle coverage is needed. Widely used lens designs naturally deliver an image circle diameter comparable to of greater than the focal length, which is then "cropped" by the film or sensor to the needed size. So all but a few wide angle lens for a 6x6 system are already fine, and not bulkier than designs for 645 format would be.
Anyway, the image circle size is not that much different: 80mm vs 70mm: we are not talking 35mm vs APS-C here!
To get an idea of how little lens design relies on matching image circle size to the film/sensor format, it is interesting to see the specs of lenses for the Mamiya RZ67 at
http://www.mamiyaleaf.com/legacy_RZ80.aspwhich is the only lens system for which I can find this data. Every lens from 65mm up covers far larger image area than even the 6x8 format that this system also supports: that 65mm wide angle lens covers 80x100mm, the 90mm normal covers 82x97mm, and so on up to 298x370mm for the 250/4. In fact every lens covers a field significantly wider than the focal length, so optically, they are all optical designs of moderately wide-angle coverage, then cropped, often massively, by the film or sensor.