Do people think resolution of the MF sensors is so low that false detail on the pixelpeep level must be introduced?
Indeed, for me at least, even the recent D800 samples, with a mere 36MP and a "smear filter", offers resolution beyond almost any non-pixel-peeping purpose.
To be a bit dogmatic and simplistic, my big print strategy would be:
(a) Always print at high enough PPI to suppress any discretization effects; at least 200PPI+ for any prints that can be approached within a couple of feet. (camera pixels/inch, not up-sampled or DPI).
(b) If that means that the prints are not as big as you want, then get more real resolution, by upgrading to a sensor with more photosites, using a multi-shot back, stitching, or whatever.
(c) If you are serious enough to pay DMF prices, don't try to fake it with inadequate PPI plus an aliasing-induced increase in accutance.