it sounds like 1) there is a problem in the keyboard Bluetooth wireless, 2) same on the laptop, or 3) wireless interference - could be fluorescent light ballast, another wireless radio close by ( i had this on my wife's laptop when we had to replace the built-in wireless with as USB version. i had to extend the USB wireless out a couple feet away, then the keyboard stopped loosing connection), a power supply that is not well shielded, or similar.
i suspect the only thing lightroom has to do with it is the keyboard is not used and is going to sleep (powersave) and does not reconnect, or gets hung trying to reconnect. That could be a driver issue if it is not an interference or hardware issue.