The cheap online guys usually ship wraps in skin tight boxes with almost zero internal clearance and precious little protection. It's a statistics thing...if a few pieces have to be replaced due to crummy packaging, it's still cheaper than actually packaging everything well. Wouldn't work for us.
When I have local shippers box and ship big pieces, I have often spent $200+. If the customer will go for it (and some can) then that's fine. Otherwise I pitch shipping just a print for local framing. That's not as much profit, but way less hassle and it can sometimes save the sale.
Always watch out for dim-weighting. There are formulas on the UPS site to calculate when you hit that wonderful dim-weight point. For instance, A 24x48 can be can be packed & shipped by UPS for something like $90, but a just a couple inches bigger anywhere and suddenly it's more like $150.
There are some short-haul shippers out there that are pretty economical...I'm told. Don't have many here the high desert, but they are more common east of the old Mississip. Also might be worth checking out messenger services, for a while I was sending framed pieces back and forth 55 miles between Albuquerque and Santa Fe and the cheapest way was actually NebArk Messengers, bless their defunct little soul. They would pickup and deliver at my door and usually made the trip within a couple hours.