Yes, wait until the printer stops and change carts. The printer will start back up and you won't notice where it stopped. All Epson's share this feature. I once had customer who ran out of yellow and waited from Friday until Monday, when he replaced the yellow, his printer started back up and no indication that it had run out. NEVER replace a cart when you get a low warning. You could be trashing as much as 1/3 or your small ink tanks.