I used to own both, the Nikon is of course more convenient, but pretty far behind qualitywise when dry scanning. It seems that wet scanning closes some of the gap, but that really is a pain.
Now, the #1 advantage of the Nikon is ICE dust removal that can save a huge amount of time, at the cost of a bit of additional sharpness. It really depends on your degree of dedication in terms of maintaining a clean environment and in cleaning slides before scanning.
DR is where the Imacon shines on hard to scan films like Velvia.
The Nikon equipped with SilverFast uses iSRD rather than ICE - it's superior in terms of user control over detection and mitigation and preserves image detail very well.
As for resolution and DR, if you were to measure both scanners using relevant targets, based on my experience with 35mm, I suspect you'd find the differences to be very small, but I have not made such comparisons myself for MF so I won't hang my neck out on that one. The depth and tonality of usable shadow detail you can obtain from these scanners also depends importantly on software, and you can do some remarkable things combining SilverFast with Lightroom, for example.
The whole idea of wet scanning scared me until I tried doing it with film cleaner on the recommendation of a staffer at LaserSoft Imaging. He was right - this makes it really quite tolerable.