OK. I am using a Canon 20D. After converting in Adobe Camera RAW I then have an RGB image which I can then capture sharpen. I then convert to monochrome (desaturate or channel mixer) and manipulate, but I have to stay in RGB to do the output sharpening. Then, finally I convert to grayscale in order to print (either with QTR or through the Epson driver on my 2200). Does that sound right?