Constant toggling of the LED certainly is not going to increase the lamp lifetime. I both spoke with X-Rite's tech support and emailed them regarding this issue. They claimed that it had never been reported before, they hadn't seen it, and it must be my computer. When I replied that it happened on at least 7 different machines running four different operating systems and on both an iSis and iSis XL, well, "we have never heard of this before."
Call or email X-Rite: It is time they heard about this problem. I, for one, do not want to have to replace a dimmed LED sooner than necessary. I do not know what minimum luminance level the iSis requires. The lifetime of bright, white LED bulbs is inversely proportional to the bulb temperature. Depending on how well the iSis heat sink around the bulb performs - assuming there is a heat sink at all - the constant flashing may not be a significant problem. If it is enough to heat up the bulb, however, lifetime will suffer.