A large part of the motivation for making Lightroom in the first place seems to have been to make a "parametric" image editor. This means that Lightroom will keep track of what you decided to do to the image, but that those changes are applied only when Lightroom feels like it (rendering to display, rendering to print, rendering to file export). Proof of this is that they changed the debayer algorithm in 2010, with the option of re-applying it on older files, and the fact that the only file stored to disk is on the order of 100s of MB, not multiple GB as one would expect with something like Photoshop.
The inner workings of how Lightroom applies those edits is (to my knowledge) not known, and probably a well-guarded secret. It seems safe to assume that the Adobe people did a fair amount of thinking, testing and refinement before they decided on how it should work. Perhaps the sharpness is applied in several stages. Perhaps it is depending on the settings of other controls. As far as I am concerned, Adobe are at full liberty to implement the underlying processing in any fashion that allows me to make good-looking end-results using a set of controls that makes sense to me.
It makes little sense that the order of sharpness/NR _processing_ should be affected by the order in which I tweak the buttons. I expect the image pipeline to be fixed, and that every time I tweak a button, all subsequent parts of the processing will be re-applied.
-h