Low relative humidity can cause ink to dry and clog the nozzles. If you've got forced hot air heating, that can be an issue. Sometimes, I just print out a file with solid patches of color that use up all of the inks -- solid black, solid light grey, solid cyan, etc. Sometimes that "primes the pump" and clears the nozzles. Living in Central Florida, where low humidity isn't an issue, has spared me a lot of the clogging problems that other people in the country have. My first line of defense would be to invest in a humidifier with a hydrostat, so that you can dial in the amount of moisture in the air.