"Know the truth?" No, but I have been using the Pocket Wizard TTL system for about 18 months now, using Canon 1D series cameras, and a mix of 580 EX II and 430 EX II flash units, along with a couple of older Canon speedlights (580 EX and 550 EX.)
The 430 EX II units work perfectly, no issues. Love 'em. Want more.
The 580 EX II units require the "flash condom" fabric cover to reduce radio frequency interference. Once you have installed the cover, and the hot shoe RF reducer, the flash unit works 100% of the time.
The 550 EX has the longest range of any flash I have tested. If you can pick these up used somewhere for cheap, they are a good choice, as they can take an external battery pack.
Using the PW system on TTL, you get exactly the same TTL flash control as with the Canon infrared system :-). In my experience, using one flash off camera through a diffuser works pretty well -- a little tweaking with the FEC in camera, and I get decent results. It's nice to be able to move around outdoors with a subject and an assistant, and not worry about tweaking manual flash output with every change. However, with multiple lights, or in tricky conditions, I have not had much success with the Canon TTL system, so I mostly use the speedlights on Manual output, and the camera on manual as well. (Maybe I'm just not smart enough to use the Canon TTL system.)
Zone Controller: I waited over a year for this thing, finally got it a few weeks ago. The good news: it works. I can adjust the output of three zones, either manual or TTL, from the camera position. The bad news is that I find it difficult to use in real-world conditions. The dials are very small, and there is no "zero" detent -- it's tough to see what the settings are even with my glasses, and tougher to make quick changes. I have color-coded my receivers with tape, and put the corresponding tape on the Zone Controller, otherwise I would not remember which flash was in which zone.
Given my own preference for manual flash, I'd probably have been better off with the Radio Popper Jr-X system, which offers remote power control of several brands of flash units, speedlights and mono lights. It's manual only, not TTL, and costs about half of the PW TTL system.
As usual, your mileage may vary. Test for yourself.