It's a difficult one to answer: at best, you can only really know your own situation intimately enough for truthful response to such a question.
In my own case, I was already married and we had two kids when I started off on my own. My wife was totally behind me in the venture and I have to say, through good times and the inevitable bad ones, she never complained or suggested I do something else. But then, we met when she was fifteen and I seventeen, so there were few surprises to come along out of the blue and rock the boat. Even our backgrounds were pretty similar and I'm sure that helped a lot too; for a start, I realised from school that we had different strengths and she was far more into mathematics and the sciences than I ever was, which even now reflects on my attitude towards digital.
As far as the work side went, she did a fair amount of business entertaining for us which went well because she was a very accomplished chef, she had seen her own parents doing the same business thing from a very young age and it seemed natural to her; she had a clear mind and very little went past her. I remember once when we were down in England because I had a calendar being printed by a firm down there: the guys took us out to dinner and towards the end they made a pitch for me to do a calendar for one of their clients. She almost choked with amusement because of the way it was done - wine em, dine 'em and then make 'em a pitch! She always found male business strategy a strange, silly business where to speak clearly and upfront would save so much time and money and confused messages. For a start, all parties would be sober and remember what went down. She never did seem to want to accept that the need for the booze stems from insecurity and that without that lubricant many can't function...
When I first started doing foreign shoots I used to travel alone with the model(s) and client, if the client wanted to come along, and it might have seemed every man's dream life. It wasn't. Working alone with a girl for a week or two quickly and inevitably brings up many unstated problems/situations. The glaringly obvious one is: if I make a play she will either respond positively or it could wreck the shoot if she takes offence. The alternative is just as bad: if I don't make a pass, will she take that as an insult? Will she think I wished I had booked somebody else? Both ways you lose and the work can suffer. So, as soon as budgets allowed, I formed an offical business partnership and we both went on trips together. It resolved the sex problem for both sides, gave the girls somebody to talk with about their spots and, better yet, gave me someone with whom to share memories of places we had worked in, which was far better than memories for and of one.
But, but and but: there were certainly times when I just knew that I would have got better results from the girl if we had not had a wife standing there helping out. It all depends on the time, mood and circumstances of the job. Some girls react very positively to verbal flirtation during a shoot whilst others just want to get on and do their job without saying much. They are all different and I suppose so are the photographers.
If anything, I believe that where a wife can be invaluable is in the client relationship, particuarly on shoots, where tempers can rise and it helps to have a calming influence present - a buffer, someone who sees both sides of a problem at once and has the personal skills to pour oil where the waters need it most!
Overall? I would do it the same way again.
Referring to Ray's comments about equipment and wives: when I was working, Ann never, ever complained when I sometimes stretched us a bit to buy something I thought we needed to make the photography more flexible. But, after I quit, she hated me to buy anything photography-related. Again, I have to admit that she was right and I was wrong. Perhaps that's why I have so little stuff anymore: I realised she was right and photographic life for the amateur does not depend on covering ever situation that life might throw in your face.