Well, I just ignore the 64bit CS4 and use the 32bit version. I have two problems, and I wonder if anybody else has experienced them.
1) The cursor sometimes becomes barely visible, and instead of showing the little hand when I type H, it shows what looks like 3 tiny crowns. When I go to an adjustment layer, Curves, for example, it turns into a line of two faint vertical bars and a plus sign. While I can still do what I need to it makes it almost impossible to re-adjust a previously placed point on the curve.
2) Using Free Transform no longer works the way it used to. I had always been able to pull on a corner handle while holding Ctrl-Alt-Shift down and get the Perspective adjustment. If I held the Alt-Shift down I could Scale the image, and if I held the Ctrl down I could distort by pulling on any handle, changing only that side of the image. Now, some of the combinations seem only to move the layer, and others give unexpected results.
I confidently figured that it was a corrupted Preferences file, so I restarted CS4 by trashing the old Prefs fle and starting a new one. Nothing changed.