Thanks for the replies.
A few answers:
Photoshop works fine at startup, when using it a while it starts to drag it's feet. Should have mentioned this before, my mistake.
Like wayne said, I don't think it's a 32bit vs 64bit problem. I'm no expert but it seems unlikely. My homesystem is similar, and there are no issues. I installed PS CS4 on another computer with a different OS version and the problems persist.
Wayne: I have more than enough available space: 800gb+. Al that storage is one 1 terrabyte drive, though.
The font isn't the problem (I wish it were that easy).....
Any and all advice will be apreciated!
thanks in advance,