As an Aperture user for the last two years, DNG didn't really fit into my workflow. When LR2.5 came out, I decided to make the switch, and at that time I read everything I could find on DNG as well as watching various LL tutorial videos.
Now I import the raw files using Bridge. Then during import, LR copies the files to DNG and makes an external backup of the original raw file. The DNGs get manually backed up on a separate external drive. LR works with the DNG, but I also save XMP sidecars for any image that gets selected to go further along in processing. I think I'm covered for most eventualities.