Hi,
In my view CCD scanners are OK for large print, I have made very good prints from scanned Velvia and Provia. The largest prints I made were 70x100 cm. The major disadvantage I have seen with CCD scanners is that they cannot handle the DMAX of Velvia (it's about 4.0). The Nikon may be better than the Minolta scanner I had. Whatever DMAX the CCD scanners handle, slide film has a low dynamic range.
What this boils down to is simple. What can be done depends on subject and film. In the best case a CCD scanner can deliver, in other cases it may be hard. I have never scanned negative film, to my knowledge it is not easy,
Best regards
Erik
An established artist friend of mine who did a 70+ piece exhibit at Ace Gallery in Los Angeles, with most prints being 7' diagonal or larger, shot MF film with a Coolscan 9000.