I've been running a dual monitor setup for three years now. (How I survived with one, I don't know!) Back when I ran Windows XP, you needed two separate cards to run two calibrated monitors, regardless of how many DVI ports a card had.
I need to replace one of my cards (the screen goes blank for a moment periodically), so I was looking at the newer GPU cards. Since Photoshop can now make use of a cards GPU horsepower, I started wondering whether two cards are still needed on a Windows box, if you run two monitors. Back on Windows XP, each card required it's own LUT, and each card could not have more than one LUT. I haven't seen anything regarding Vista.
Thanks for the help.
Nemo