[font color=\'#000000\']There are a lot of little roads leading up into the Sierras from the 395, virtually all with hiking trails at their ends - be sure to take at least one or two of them. My favorite, mentioned by a couple of people already, is highway 168 leading into the mountains from Bishop, with branches to Lake Sabrina, South Lake, and North Lake - I think the most photogenic of the three is South Lake, and a great trail (to Bishop Pass, about 5 miles or so each way) leaves from there, with more little lakes along the way.
I also second the recommendation for Death Valley, and the one for the bristlecone pine forest in the White Mountains - not just for the trees, but for the sweeping vistas of the east wall of the Sierras (and yes, it really is a "wall").
Can't say much about camping, since I don't do it myself, but there are campgrounds scattered about in the region (maybe a web search will turn up info?). There are also motels in the towns up & down the 395.
Lisa[/font]