Dear Evgeny,
I see what you mean, now: an image is worth a 1000 words!
These what you call "black pixels" simply indicates a pattern following a misregistration due to some movement or vibrations during the process of the 16 shot.
The 16 shot mode is critical: one has to have a very stable floor, a heavy and stable stand (tripod not recommended), all machines likely to produce some sort of vibrations in the room or nearby rooms should be shut off (e.g. AC), walking during the process should be avoided, etc ...
I can tell you that I twice had such a problem with AC elements on the ceiling, and the other on the floor, about 15 meters aways from the shooting place. I had as well problems with thiny vibrations on a groundfloor although having a very stable concrete floor.
Therefore, I am convinced that vibrations are your problem here.
Best regards,
Thierry
This is a 100% view of the 4-shoot image. It's better to see it at 200% to compare to the 16-shoot image below
This is a 100% view of the 16-shoot unprocessed image. Please see darker pixels on the right side of the doll. There is no such pixels on the left side.
I don't know what is it. It not looks like a shift during 16 exposures.. Comments?