If you hand held a landscape shot at say 1/200th, would it be sharp at distance?
The general rule used to be that the minimum shutter speed for hand-holding was one over the focal length = 1/125th of a sec for a 125 mm lens: with high res film or smaller pixels it gets more critical, but the rule held for all formats, so, with a larger format with longer lenses for the same angle of view, you have to use faster shutter speeds or a tripod.
You could read Harold Merklinger's "The ins and outs of focus" and work out what size of subject detail you can expect to resolve at what distance for your camera and lens (and confirm by experiment) ... and experiment to find out how much camera shake you need to allow for (in degrees) and work out (trigonometry) at what shutter speed the camera shake is likely to be the limiting factor.
If you make the normal mistake of using wide angle lenses for landscapes, the rule would indicate that you should be OK at 1/200th if you are using anything smaller than 10*8".
... but I have a 640 mm Novoflex non-tele lens with two pistol grips and a shoulder support, and I could consistently hand-hold it at 1/125th (especially if I had my elbows on the ground), and I find that my Hasselblad will not produce sharp pictures @ 110 mm unless it is on a tripod with the mirror locked up!
I realize that a 1 degree move at the subject can equal hundreds of yards at a distant object, for example, aiming at the moon with a .00009 discrepancy could mean you miss the moon by hundreds or thousands of miles. I'm wondering if this would translate into the distant object moving at a high enough speed to blur it at higher, usually considered fast enough shutter speeds to stop action, such as 1/500th down to about 1/200th?
If an aeroplane is moving at 500 mph, and you want it to look sharp so that you can see the windows, the blur (in feet or m at the subject) is not affected by the distance. If the plane is just a dot in the distance, you do not need to see the windows!
The beauty of digital is instant feedback, so you can suck-it-and-see, immediately, if you used a fast enough speed - the angle of movement is relevant, of course, and you might be able to pan: find a busy road, railway or airport and experiment.
If you are into photographing steam trains, and your subject only comes past once a decade, you need to think about it before hand and you might turn up the ISO if a cloud came past at the wrong moment... and you need to have some idea how fast the train will be traveling - steam trains pulling up hills or pulling out of stations move slower, and make more steam.
Of course, trains are a good argument for tilt/yaw, as you can position the plane of sharpest focus where the train is going to be (assume it will stay on the track!) and use a larger aperture and a faster shutter speed without increasing the ISO. (See Merklinger's "Focusing the View Camera".)
If you want a fast, distant subject sharp, and the foreground also sharp, you can take two exposures and combine them in PhotoShop.