in my experience, the 24-105 and 70 200 f4 are good lenses, particularly in the center. but for maximum resolution, primes are better - better resolution in the center, and much better resolution in th edges and corners - the 50 1.4 (stopped down to at least f4), 100 macro, 200 2.8 and 300 are all noticebly better than the zooms.
however, microadjustment is still essential. although i've generally found Canon primes to pretty good, when i tested the 300 f4 i discovered why i'd been so disappointed with it in the past - it needed a +15 correction (other lenses all between +4 and -4 so i think the body focuses accuratel). preliminarily, it seems like telextenders degrade the image proportionally more on the 5D2 than 5D even with microadjustment of the focus, but i'm not really sure yet (that microadjustment remembers the lens-extender combination is good, because the extenders can ntroduce significant focus shift)
i put the mirror lockup at the top of My Menu, reserving the custom functions for other purposes (including HDR)
i certainly agree that liveview with magnification is amazing with the high resolution screen