I agree with Andrew Rodney about not using "Simulate Paper Color" while the panels, menus, or any other source of white are visible on the screen. However, I find it difficult to edit the softproofed image without Paper Simulation, then check the box and switch to full frame viewing.
Would it be so difficult for Adobe to either reduce the whiteness/brightness levels in the pallets and dialog boxes, as in the adjustment and layer panels, to a level that would be less bright than the paper-simulated white would be? (Similar to what is done in LightRoom?
Or, as in the options to set the color of the Gamut warning, masks, guides, etc, how about an option to choose the text and pallet background colors?
Either way, it would increase the usability of the Simulate Paper Color option in softproofing.