I've just spent a day working with the new Adobe Beta camera profile builder, & have come up with some tentative issues/results that I'd like to check out against other folks' experience:
First, isn't this basically a LENS profiler, not a camera profiler? I use different vintages & brands of lenses in Leica M mounts, & they differ in the way they render color. I'd also noticed different renderings with new Canon L zoom vs. older Canon primes.
Second, are the new Standard profiles improvements for your particular camera/lens? I experimented with the lens I use most of the time (28mm asph Summicron on Leica M8 - a fairly common pairing. I shot the ColorChecker in north light & indoors. I found that:
--The older 3.3 & 4.4 profiles & the new custom profile yield pretty close results.
--The new Standard profile is noticeably different from the above three. The Orange patch is too vivid, & the Blue too purple. The orange overstatement messes up skin tones (as others have noticed), & the ColorChecker pamphlet says the B shift is a definite sign that the profile needs first aid.
--So I concluded the new Standard profile isn't really an improvement for this camera/lens.
Third, C1 v.4 (with DNG Neutral profile) was a steady runner-up to the custom profile - when I tried different images of skin tones & a colorful street scene, default settings were always a bit flatter but always readily adjustable in PS, & were more accurate than the new Standard profile.
Fourth, I'll generally be using the new custom profile, but it's no magic bullet. The older profiles rendered skin tones a little too M, & the custom one is just a bit Y, but it pretty consistently looked best in colorful scenes. (I didn't try a landscape to check greens.)
Fifth, for color-demanding work such as product photography, I suppose you'd have to shoot a ColorChecker & make a profile for every scene!
Sixth, one very clear conclusion: it's really easy to use the new profiling software.
Granted, most folks are using Canon or Nikon, so my day of experimenting doesn't prove anything-in-general. But it's a tip-off that the new Standard profiles aren't necessarily 'better.' Instead it would be a good idea to compare the new Standard ones with 4.4 & with custom profiling.