So Jeff, I use a Canon 1Ds3 which of course has 21 MP. Do you suggest an alternative for us?
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Not to put words in Jeff's mouth - but... as a user of LR and owner and use of 1DS MK3 myself I have found that settings of around 60 for amount radius 1 [which is roughly the same as radius .5 in unsharp mask I think] and detail of about 40 is a pretty good start for most landscapes provided you have a good capture.
You can easily of course make a preset for this as I have done and it becomes the default sharpening for 1DS MK3 files.
Experimentation is key with this stuff and its still image dependant - so I always season to taste for my select images.
I still use PKS for my output sharpening in CS3 as LR doesnt yet have soft proofing.
Thats my thoughts and current technique.