If anything your print will look a little sharper under plex, glossy surface glazing slightly increases the perceived contrast of the print underneath.
Acrylite-FF is a great plex that is extremely clear, color-free, ripple free, and cheap. Dollar for dollar is very superior to same-priced glass. Locally I pay about $68 per 4 x 8 foot sheet, and my supplier will happily make (almost) any number of cuts in it for free. If sell able pieces of material are left after making the cuts, they usually only charge me for the actual square footage I receive, there's a little give & take there.
The zero-reflection Optium is amazing stuff, but be prepared to pay an absolute minimum $60+ per 13x19" cut. If your frame will be handled by the typical dunces who run photo-contests, county fairs etc, don't use it because it will surely get scratched by such folks.