Photoshop adjustments transfer to Lightroom

[idenford]

I have spent the entire day viewing the printing tutorial with Jeff and Mike.
I have made some prints that I like and have downloaded the sharpening plug in.
Once you make your adjustments in Photoshop, including sharpening, custom profiling and soft proofing, and you transfer the file back to Lightroom, do you lose and of the changes you've made to the file if you do a few more tweeks of that specific psd file back in Lightroom?

[janisr]

I have spent the entire day viewing the printing tutorial with Jeff and Mike.
I have made some prints that I like and have downloaded the sharpening plug in.
Once you make your adjustments in Photoshop, including sharpening, custom profiling and soft proofing, and you transfer the file back to Lightroom, do you lose and of the changes you've made to the file if you do a few more tweeks of that specific psd file back in Lightroom?
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I don't suggest you to use lightroom for printing - yes, it is easy to move the photos around the paper , it is easy to manage your prints, but it sure messes with colour! Three prints ar good, suddenly the 4 is with wrong color!