You don't necessarily need to use your sharpest lens---if nothing but image quality counts then better use your longest lens and shoot a multi-row panorama.
Which a longer lens, you'll need more shots to cover the required field-of-view, you'll get more megapixels and thus, more detail in the final image, and you'll be forced to pan and tilt your camera around the no-parallax point (commonly but falsely called the "nodal point") with higher accuracy.
Setting up your camera so it will pan around the no-parallax point isn't too hard; a simple focusing rail will do if you don't have a dedicated no-parallax panorama tripod head. But tilting around the no-parallax point is pretty difficult, and tedious to achieve without special equipment. So maybe you'll want to use the lens which, in portrait orientation, will cover the required field-of-view vertically so you'll get away with a single-row panorama.
-- Olaf