With C/A, I usually find a small detail (like a leaf or a small stone) near a corner of the frame, since it's easier to see C/A in the corners than the center. Zoom in to 1:1 or even higher magnification (the Ctrl+0 and Ctrl/Alt+0 key combos are most helpful). You want to hold down the Alt key (on a PC) while using the C/A sliders, which filters the colors down to what the slider is actually adjusting. Then just adjust the slider until the colors on both sides of the subject detail look the same. If you hold down the Alt key, it's really easy to see. Then go to the other slider and repeat. It's a good idea to look around the frame and verify that the adjustment is good everywhere, because other forms of fringing sometimes interfere with C/A.
You won't see the benefits in small prints a lot of the time. But if you print large, or crop a lot, it can really make a big difference. I use a C/A correction on most shots, generally because I can only afford crappy lenses, and most of my shots need some. I don't get very worked up about distortion either, because that's easy to correct too.