Not really. I think a fair comparisol can be performed only after both pictures have been enhanced usign the best technology and knowledge one can reasonable afford. That one is important because using the best technology and expertise is beyond my means.
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I think that that´s a fair way of looking at the question - why would you ever work either system to anything less than your best possible level?
Of course it has to be at a subjective level - there`s no other way where anything else makes sense, for you might as well then start comparing 8x10 transparencies with 35mm, 6x6, 6x7 or anything else that´s around; Olympus with Canon FF etc. etc. (I do have to admit that some here are already doing this, so perhaps the less said the better!)
In the end, unless you have very deep pockets or an ultra friendly dealer who wants to get to know your sister better, you just have to soldier on and make the most of what is.
Enjoy and don´t waste life looking for perfection: it´s an illusion; trust me, I´m unfortunately old enough to have discovered this.
Rob C