Purely for the camera gear..i.e. no lights etc..my dakine sequence takes my 500 hasselblad and two lenses (three at a squeeze) plus my 5d and one zoom lens with all film, spare film back, hoods, meters, cards, batteries, etc etc, and the tripod fits securely and quickly into the axe slot on the side.
The top and back leaves room for food, maps, jacket and other stuff.
This has all gone up mountians in switzerland and wales in the past few weeks with no problems and the fact you open it up from the back means setting it down on muddy, snowy, (and even copper stained rocky ground!) etc is no problem.
Certainly worth a look...and its good for skiing with too!
Marc