I use it virtually only hand-held. I use it mainly with environmental portraits (people in their natural habitat) and products (shoes, bags & other accessories). I do around 50K images this way per year.
I have the following lenses in the bag. ZF25/2.8, ZF35/2.0, ZF50/1.4, ZF50/2.0Macro & the Nikkor AF 85/1.4.
The Aptus performs excellent with all these lenses. It is not just the ISO25 but all other things as wel, 16bit colors, 12stops DR, etc.. that make the difference.
Other lenses that I use or have used are: 20/3.5, 28/2.0, 55/2.8macro, 55/3.5macro (AI, Pre-AI, AIS), 60/2.8macro, 105/2.0, 135/2.0DC, 180/2.8, 70-180Macro.