In my opinion the picture is over-sharpened. There are obvious halos on high-contrast edges (shirt/neck, shirtsleeves, eye whites, etc), the specular highlights on the skin are exaggerated, and the hair also looks a bit crunchy in places.
You mention using radius=10, amount=65; that radius setting is far too high IMHO, and is the cause of the excessive halos. Try using a smaller radius and a larger amount. I probably wouldn't ever use anything above 1 or 1.5 unless I was doing local contrast enhamencement with a really large radius (like 40-50).
My workflow for D2x landscape images (or other images with fine details) has been to disable sharpening in the RAW convertor and then do my "capture" sharpening as one of the first steps in Photoshop. I sharpen the L channel in LAB mode, using a duplicate layer so I can mask if necessary. The parameters I typically use are radius=0.3, amount=350, and threshold=0. Sometimes I might bump the radius a tenth or so and drop the amount, it just depends on the image content. These settings are for clean images; if you have a noisy image these settings will exaggerate the noise so you'd probably need to increase the radius and threshold, while lowering the amount.
More recently I've been evaluating the new sharpening in ACR 4.1, so I've been using some weak sharpening in ACR (Amount=30, Radius=0.5, Detail=60-70). Then I still do the lab sharpening step described above, but I cut the amount in half to about 150.
For people pictures I usually use FocalBlade since it's pretty easy to get good results without over-sharpening the skin. But if I were to use straight USM I'd probably start with amount=150, radius=1-1.5, and threshold=2-4.
BTW I think it's worth pointing out that the optimal radius and amount settings are going to be dependent on image resolution. The parameters you use for a 10-12mp image are going to be very different from what you'd use for an 800x600 web JPG. For instance when I resize JPG's for the web I usually do so using Bicubic Smoother, and then apply USM with amount=70, radius=0.3 or 0.4, and threshold=0 or 1.