Sounds like we use similar bag strategies for travel, Dave. I always pack a Zoom Traveler 6 from
Tamrac in my suitcase while using a larger bag for onboard carry of gear. It is just about perfect for my needs of a location or walkaround bag. I normally carry a D2X, SB-200 strobe or two, Sekonic light meter, 12-24mm, 24-120mm, and either a 105 macro or 80-200mm. The 80-200 is a squeeze with everything else. Lots of rooms in pockets and zippered pouches for cords, filters, batteries, strobe accessories, tool, memory cards, and more.
Best of all, I think, is the extra bag's utility inside my checked luggage for containing and organizing all the photo accessories I don't include in carryon. It's sure nice to have all that stuff corraled and at my fingertips right away when I reach my destination.