I've used several and they are all plug 'n play. You will need to know the start-up sequence; some require that the laptop be up and running before the projector is turned on; some don't. Essentially, all the projector does is take the shot that would normally be showing on your laptop screen and project it. So everything (mouse, keyboard, etc.) works as it normally would, except that your screen is being projected. If your screen saver is a Playboy centerfold, you might want to change it, depending on the audience. 8-) Mine is usually used at academic meetings, and I always make sure that I have a USB cord with me, and I also usually bring along an extension cord...just in case.