do want to print larger than A4, as well as B&W, which is unsatisfactory on my current printer.
The 2200 had many sterling qualities but among them was not colour accuracy. Epson made a huge improvement both in linearizing its drivers and in reducing unit-to-unit variance ... with the next generation after
the 2200. The upshot is that you're likely to find it impossible to eliminate some colour cast or another to various parts the greyscale even with custom profiles. In fact, the European 2100 came with a special software app - Grey Balancer, or some such - dedicated to just that task. For printing colour images - well, let's just say some folk had better luck with their 2200s than others.
That said, there are alternate ink sets available that many wrote highly of, if you want to go that route.
Are there any issues that I need to be aware of? Ink usage is important!
I don't remember that the 2200 used an unusual amount of ink per job. The problem is that the cartridges only hold about 15ml of ink, so if you print larger than A4, you tend to find one cartridge or another perpetually needing replacement. Not a show-stopper: just less than ideal.
My own experience is that you'll quickly recoup the higher initial outlay for a more modern A3 printer just from what it will save you in custom profiles, alternate ink sets, endless test prints, and/or a pricey RIP.