the e75 is as the aptus one stop more sensitive. i use only the lowest iso setting with both backs, although certainly you can go higher ( maybee up to 100/200 iso, depending on your approach ). for long time exp. this does not make sense, cause the lowest setting will have the lowest noise level also, so iso50 with 30 sec. will have less noise than iso100 with 15sec. with the e75. no cf issue the e22, nomore cf issue the e75 also.
you can use the e75 with good rresults upto 30sec, the e22 same with lower iso25. noise level still is very low than.
the e22 is nearly free from any farbshifts, the e75 is less geood here,- but after working with whiteref. shots i changed my style with the e22 also and use the white shadings now also for it, cause i became more sensitive for these farbshifts and the e22 is not perfect also, so the image quality improves ere also with white shadings.
the 33mp give enough freedom for any cropping, thats a big advantage. the color rendition of all kind of tungsten or fluorescenz lights are much better with the new chip. but the e22 is a great back, esp. for landscape and architecture also.
sw. workflow and quality is great, at least with the software i use from brumbaer.