I think it's easy to overestimate the difficulty of driving on the other side of the road. The main problem I encountered was estimating the distance to the kerb.
I took our Spanish car (LHD) over to Britain many times, and contrary to my expectations, the driving problem was not cities and passing buses, it was tight rural roads in Scotland. It's quite an existential thrill watching a huge timber truck come thundering towards you on what starts to feel like a path. I was convinced that I was driving up on the left-hand kerb, but as it consisted of boulders, I guess it was just an illusion.
Cities anywhere, unless you already know where the hell you are going, are a nightmare: knowing which lane to choose several hundred yards away can be difficult, despite signs. Trafiic isn't usually inclined to be gentle and giving, unless you have an L plate... now there's an idea!
Weather is most likely to be the problem numero uno. I lived in Glasgow for about thirty years and saw Loch Lomond in sunshine twice - thrice at the most. To be fair, I wasn't there every day, but you get the picture.
The Trossachs, mountains/hills north of Glasgow, were beautiful on rainy days: we selected such conditions to guarantee us a parking place where we could enjoy a picnic in peace.
I have never used satellite navigation; I don't think we'd get along very well.
Rob