I just set up a Canon pro-2000 (replacing an Epson 7900 that died of a blown yellow channel- if anyone wants a 9-channel 7900 for Piezography or other alternative inks in the Boston area, PM me!).
Kudos to Canon for a remarkably easy printer to set up! It's big and heavy, and takes two very strong people to lift up the printer and get it on the stand (but that's true of anything 24" wide). The rest of the setup and initialization is very well documented and largely automated. I've installed quite a few LFPs over the years, and this is one of the easiest. For more detail, Keith Cooper's excellent setup article at Northlight Images has a ton of pictures
With any stand-mounted printer, the first step is to build the stand, and this is an easy one. You really can't put it together wrong, and it bolts together with four Allen bolts turned with an included Allen key. After building the main part of the stand (the print catcher comes later), you turn to the printer assembly manual and drop the printer itself on the stand - the locator pins are very good, and the printer attaches to the stand with six bolts.
The print catcher is next, and it is much easier to set up (and harder to break) than the Epson equivalent. The pieces are quite a bit sturdier and the front arms can move to a wide range of positions while the back can attach in front of or behind the printer, allowing a conventional basket catcher, a ramp or a flat surface...
The next step is ink installation (12 160 ml cartridges - keyed so they're hard to get in the wrong slots), then a drop-in printhead installation. After installing the ink and printhead, the printer asks for the included paper for initial alignment. The alignment is automated - no deciding which of several patterns offset by a fraction of a mm is correct. There are two quirks in this process. First, the printer will ask for the first sheet of alignment paper almost as soon as the printhead is in, then sit and gargle ink for nearly an hour before it prints the alignment pattern. This is documented on the setup sheet, but I've never seen any other printer do it in this order - usually, they prime the lines and head, then ask for the alignment paper. The second quirk is that Canon supplies sheet paper for alignment - this is a roll printer! Fortunately, it's pretty easy to load sheets on this thing - I have cerebral palsy, and I did it one-handed easily enough without ever getting a sheet askew. The alignment process takes five sheets of paper, so tell it "yes" when it asks if you want to keep printing.
After it aligns itself, it asks how you want to connect it. Mine's on wired Ethernet, which it found on its own. Annoyingly, my Mac's in the shop, so I can't tell if it's really on the network, other than that it says it is. Apple, give me my computer back!
The final step in setting the printer up is to perform a color calibration. This is a linearization of the printer so all Pro-2000s (and the wider models)will behave similarly, NOT an ICC calibration. It's easily found in the maintenance menu on the touch screen, and it takes one more sheet of the included paper - the printer prints, then reads a series of color patches and it's done. Canon has done this for years, and it's a help with using paper manufacturer profiles. As long as you've linearized your printer, and the paper manufacturer has linearized theirs, they should be very close. Epson's factory linearizations are pretty good, but there's no way to keep up with any drift as the printer ages. The other advantage to Canon's process is that all the 12-ink models (Pro-2000, Pro-4000 and Pro-6000) should all be the same. If you own a Pro-2000 and occasionally want to make a 44-inch (or even a 60-inch!) print, all you need is a print shop with the larger printer (ideally with the same paper and profile, but a similar paper will do if both have correct ICC profiles).
All in all, one of the easiest big printers I've set up and I can't wait to actually print when my Mac comes home- see my accompanying post for more thoughts about the state of the big printer market in general...
Dan