Before you start measuring anything, when you get to the screen that allows the measurement, there is a button on the screen under the image of the chart you will measuring that says "Calibrate". Put the colorimeter on the platform that has the white calibration patch (open it if it is not open by sliding back its cover) the click on the "Calibrate" button under the image of the screen to be measured. Once it is calibrated, a red box will appear around the area you can start measuring, and it will shift with each row you finish measuring.