I realize this is a noob question but the directions with i1Profiler are somewhat lacking.
Dave
It's a perfectly valid question, and your statement about directions being "somewhat lacking" is a masterpiece of understatement. X-Rite is one of the of the most irresponsible outfits in the industry and the manner in which they are selling this product is both disgraceful and counter-productive.
Rant out of the way, Andrew is right - scan in dual scan mode. Then build three profiles, by going back to the measurement tab and selecting the successive M0, M1, M2 conditions and reverting to the Profile tab to build another profile with that condition selected. When you save the successive profiles, indicate in the profile name whether it is an M0, M1 or M2. Then make three test prints, one with each profile and retain the one that gives you the best results. I use the accuracy testing procedures I described in my paper reviews of this website for doing that. There are also small variances of gamut between them, which are normally safe to ignore. For me, the accuracy of colour and tone rendition are more important. If the paper you are using contains OBAs, there is a chance that M0 and M1 profiles will create a yellowish version of white. This is an over-correction of blue created by the reading of the UV from the action of the OBAs. For these situations, selecting the M2 profile will usually give more pleasing results.