Two days into the discussion and nobody has mentioned f-stop yet
Anyway, here's my suggestion, super light and super modular / flexible, however you want to call it. I use a system of Tenba pouches in mine, which makes packing and unpacking sure easy and saves me from forgetting stuff from time to time. When I pack, I just move the pouches from my dry cabinet into the bag, and do the reverse when I unpack after a shoot. All the bits and pieces of accessories are already in those pouches stacked away between lenses and backs.
The good thing about the f-stop is that it doesn't look like a camera bag (which often says "steal me") and it also wears much more comfortable during longer walks and I've tried many photography dedicated brands to find out myself and came back to the f-stop every time.
The back opening design is also very handy, and I know this has been discussed many times, but I cannot emphasise enough, sure, it doesn't really matter if the bag is sitting on the pristine carpet of a brand new MiuMiu store, but when it's in the mud and snow, it sure make a huge difference (and I admit, I have a bit of OCD......okay, okay, I have severe OCD).
When traveling, I just keep everything in the bag and put the tripod in a small carry-on size suitcase together with my other stuff and just push the whole thing through the airport. For longer trips, I'll put the tripod in my checked luggage and carry the f-stop on my back.
And some behind the scenes shots:
At the moment, I have a Tilopa with a modified Cine Master ICU inside for my ALPA system (rhigh now it fits the 12MAX body with 4 lenses and digital back). Modified because I needed the depth in order to put the Max camera body sideways without it protruding into my back.
As currently configured, I would easily fit in the Phase One XF camera and 4 to 5 lenses plus filters, batteries and carious accessories. On top of this, there's still space for my wallet, a fleece and a jacket.
Of course, being an f-stop, you could go for a smaller ICU or smaller bag to suit your needs.