The complaints about Lr's handling of Fuji files are much quieter than in the past.
Returning to a pre-Lightroom "workflow" of multiple apps holds very little appeal, and I also judge the results by examining the final print rather than pixelpeeping. So I certainly haven't given up sharpening XT2 files in Lr. But by comparison with Nikon raw files, for example, I do notice how one needs to fine tune the sharpening for each image (or group of similar images) rather than setting a default and largely sticking to it.
I was able to get Lr to the point where it sharpened files from my X-T1 quite satisfactorily. The jump to the X-T2 with a 50% increase in resolution definitely changed things for me though. All I could achieve was blah/average results in Lr before the "wormy" look set in. Using Nik Sharpener definitely provided a significant difference for me using the Pre and Output sharpener.
As you say it does depend a lot on subject matter. My night photography gets by with the X-Pro2 settings that Pete Bridgwood recommended. Highly detailed landscapes that I've been working on though require more attention than that.
I generally confine myself to 100% pixel peeping but with Lr and the X-T2 I feel compelled to look at 200% to ensure I avoid the "worms". Using Nik Sharpener Pro with the suggestions provided by Dan Hughes video has made a significant difference for me. There I'm automatically zoomed to 300% to ensure things don't get out of hand (over sharpened).
Yes, I do print. I use my Epson SC P800 and print up to 17x22 routinely.
Do you print from Lr? What output print sharpening do you select for that, if you use Lr?