There's always a way out. Booze. Drugs. Swallowing your gun. . .
It also has a high murder rate per capita largely due to the booze and the drugs.
There is an interesting (recent) book about the general area around Clarksdale by a British author who buys an old house and moves in. It is called Dispatches from Pluto by Richard Grant. It gives a very even handed outsider's view of a region that is deeply complex and defies easy stereotypes.
The amount of extraordinary people who came from this region is legendary and hard to explain.
They also have world famous tamales.