To address the gorilla in the room, not mentioned, this is a subject that has had heated, and endless, discussion before. At the risk of arrows, a brief summation might be put as follows:
- early CMOS did not equal the rendition people were getting from CCD. Whether that was the sensor, its size, the A/D conversions, lenses, or software remains unclear.
- middle generation CMOS (say up to 2-3 years ago) got better, but there was still a difference
- current generation CMOS, both on 35DSLR and MFDB, is much much closer, and offers significant ISO advantages.
Some say there is little or no difference, others still see something separating the two. Of course, lenses and other things can factor in here, but there is no doubt the gap has diminished. Very difficult to say if its significant or not; depends on many many factors.